
Splice (2010)
“She's not human...not entirely.”
Director: Vincenzo Natali
Overview
Elsa and Clive, two rebellious young scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators — only to have that bond turn deadly.
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Top Billed Cast

Adrien Brody
Clive Nicoli

Sarah Polley
Elsa Kast

Delphine Chanéac
Dren

Brandon McGibbon
Gavin Nicoli

Simona Măicănescu
Joan Chorot

David Hewlett
William Barlow

Abigail Chu
Child Dren
Doug Hicton
Lab tech (uncredited)